There is a rising concern that acetaminophen may adversely affect lung health. Hence, the present retrospective study examined if acetaminophen, compared with cyclooxygenase (COX) inhibitor alone for patent ductus arteriosus (PDA), increases the mortality or respiratory morbidity risk in extremely preterm infants.
The study observed
This study shows that treatment with acetaminophen versus COX inhibitor alone for PDA does not increase the composite outcome of death or BPD in extremely preterm infants. There is a need for further evaluation of whether acetaminophen for PDA increases mortality.
Jensen EA, DeMauro SB, Rysavy MA, et al. Acetaminophen for Patent Ductus Arteriosus and Risk of Mortality and Pulmonary Morbidity. 2024;154(2).
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