Assessing the Role of Serum β-hCG Levels as a Predictor of Pregnancy-Induced Hypertension
Published On: 26 Feb, 2025 12:41 PM | Updated On: 26 Feb, 2025 12:45 PM

Assessing the Role of Serum β-hCG Levels as a Predictor of Pregnancy-Induced Hypertension

Pregnancy-Induced Hypertension (PIH) poses a serious risk to pregnant women and is associated with severe outcomes for both mother and fetus. The present study examined the link between serum β-hCG levels and the likelihood of developing PIH, with the goal of identifying elevated β-hCG as an early indicator for PIH.

This cross-sectional study involved 100 pregnant women aged 20 to 40 years, between 14 to 19 weeks of gestation. Participants were categorised by age, socioeconomic status, and occupation. Blood pressure and β-hCG levels were measured and analyzed.

The outcome demonstrated:

  • The average age of participants was 27.6 years, with 53% of women had gestational age of 18 weeks at delivery. 
  • Normal blood pressure was recorded in 61% of the women, while 39% were at risk for PIH, categorized as mild, moderate, or severe PIH.
  • A correlation was found between higher serum β-hCG levels and the severity of PIH. 
  • Additionally, patients with PIH exhibited significant pedal edema and proteinuria, which influenced their blood pressure and β-hCG levels. 

To conclude, increased β-hCG levels can be considered as an early predictor of PIH, allowing for timely interventions. Regular monitoring of β-hCG could enhance prenatal care and improve outcomes for both mothers and infants.

Source: Sansare S, Kulkarni M M, Kulkarni J, Kathpalia S, Early prediction of gestational hypertension using β-hCG Levels: A cross-sectional study in a tertiary care hospital of Maharashtra, India. Indian J Obstet Gynecol Res 2025;12(1):16-20.

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