Budd-Chiari Syndrome in Children in Children

Budd-Chiari Syndrome in Children in Children

  • There is limited data on pediatric Budd-Chiari syndrome (BCS), hence diagnosis may be missed.
  • A high index of suspicion and adequate work-up is needed. ‹ Adolescents and infants represent unique groups.
  • Complete prothrombotic work-up should be done in all, up to 50% have multiple causes.
  • Anticoagulation is difficult as there exists no data on direct oral anticoagulant (DOAC) in BCS in children.
  • Expertise in interventional radiology is required for the treatment of BCS in children. Innovations in technique and efforts to limit radiation exposure are needed. 
  • Angioplasty of the hepatic vein (HV) is associated with a high failure rate. When feasible, HV stenting should be preferred over transjugular intrahepatic portosystemic shunt (TIPS).
  • Inclusion of shear wave elastography (SWE) with color Doppler ultrasound (CDUS) examinations both in the pre-treatment evaluation and follow-up after RI helps indeciding therapy, monitoring response and detection of recurrence.
  • Long-term monitoring for hepatopulmonary syndrome and liver SOL including HCC(including AFP) should be done.
  • There is an urgent need for consensus guidelines on BCS in children.

Dr. Anshu Srivastava

Dr. Anshu Srivastava is an Professor in the Department of Pediatric Gastroenterology at Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India. She has completed her basic medical training and MD in Pediatrics from King George's Medical College, Lucknow and then got trained at SGPGIMS in Gastroenterology with DM degree. She has been awarded the Prof SR Naik award for Outstanding Research Investigator for the year 2014, the Dr Alex Mowat award for best hepatology paper in ESPGHAN 2009. She has published 15 book chapters and over 125 research papers in peer reviewed international and national journals of repute.


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