Comparison of Ovulation Detection Using Urinary LH Surge Kits and Transvaginal Sonography

The aim of the current study was to estimate the effectiveness of urinary luteinizing hormone (LH) surge kits in comparison to transvaginal ultrasonography (TVS) for detecting ovulation in women with anovulatory infertility undergoing induced cycles. In this prospective observational cohort study, 144 women aged 18-35, treated with letrozole for ovulation induction, were randomly assigned to two groups: one using urinary LH surge kits and the other undergoing follicle monitoring via TVS.

Results indicated that letrozole did not adversely affect the endometrial lining, and the average diameter of the induced follicles was 22 mm. Ovulation occurred later in induced cycles compared to natural cycles (average day 16). Additionally, around half of the participants had a body mass index (BMI) above the WHO-recommended levels, averaging 25.28 kg/m². The number of letrozole cycles, required doses, and pregnancy rates were statistically similar, with rates of 10.26% in the LH surge kit group and 18.19% in the TVS group.

To conclude, while TVS is a reliable and precise method for ovulation detection, the urinary LH surge kit, despite its subjective nature and potential for error, can serve as a viable alternative in specific scenarios, particularly for women in remote areas or those hesitant about invasive procedures.

Source: Verma A et al. Evaluation of ovulation by urinary LH surge kits versus transvaginal sonography. Indian Journal of Obstetrics and Gynecology Research.2024;11(3):358-363. https://doi.org/10.18231/j.ijogr.2024.066