IJCP Editorial Team
Cryptogenic Acute Hepatitis: An Enigma – How to Approach?
When the initial evaluation is nondiagnostic, then additional history is essential. AST and ALT levels help guide the evaluation.
Acetaminophen should be strongly suspected with high ALT and AST, recent medicines (antibiotics), supplements, vaccinations.
Test for herpes viruses, COVID-19 and other viruses as clinically indicated. Consider retesting for autoimmune hepatitis (AIH).
Make sure that ferritin is not just an acute phase reactant.
Consider N-acetylcysteine (NAC) with severe hepatitis. If developing acute liver failure, NAC has shown survival benefi t in ALF with Grade 2 HE and should be strongly considered. Refer for liver transplant if appropriate.
Perform a liver biopsy when diagnosis is unclear or to confi rm AIH or malignancy or other etiology
IJCP Editorial Team
Comprising seasoned professionals and experts from the medical field, the IJCP editorial team is dedicated to delivering timely and accurate content and thriving to provide attention-grabbing information for the readers. What sets them apart are their diverse expertise, spanning academia, research, and clinical practice, and their dedication to upholding the highest standards of quality and integrity. With a wealth of experience and a commitment to excellence, the IJCP editorial team strives to provide valuable perspectives, the latest trends, and in-depth analyses across various medical domains, all in a way that keeps you interested and engaged.
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