Polycystic ovary syndrome (PCOS) affects millions of women worldwide, often intersecting with challenges like weight gain, insulin resistance, and infertility. While dietary interventions are widely recognized as a cornerstone of PCOS management, their effectiveness in women with a body mass index (BMI) ≥ 25 kg/m² has remained unclear—until now.
A recent meta-analysis sought to clarify this by reviewing nine randomized controlled trials (RCTs) involving 559 participants. The findings are compelling: women with PCOS and elevated BMI saw significant improvements in weight, metabolic markers, hormone levels, and fertility outcomes when following structured dietary plans.
Among the various strategies, calorie-restricted diets (CRDs) emerged as the most effective and practical option. These diets promote sustainable weight loss and maintain balanced nutrition, improving long-term adherence. Low-calorie, low-carbohydrate, and low-calorie diets combined with extracts also showed beneficial effects, though they are recommended as secondary and tertiary options.
Interestingly, other diets—such as the Mediterranean and very low-calorie diets—yielded mixed or inconclusive results, primarily due to limited data and study variability.
In conclusion, for women with PCOS and a BMI ≥ 25, calorie-restricted diets offer a clinically supported path to improving both metabolic health and fertility outcomes. As research continues to evolve, personalized, evidence-based dietary plans will play an increasingly vital role in the comprehensive care of PCOS.
Source: Reprod Med Biol. 2024;23(1):e12607.
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