Familial Hypercholesterolemia Diagnosis and Management

Published On: 17 Aug, 2022 12:57 PM | Updated On: 30 Oct, 2024 6:03 PM

Familial Hypercholesterolemia Diagnosis and Management

  • Familial hypercholesterolemia (FH) is one of the most common and single severe gene disorders, affecting approximately 30 million people worldwide.
  • One baby with FH is born globally every minute.
  • While statins and ezetimibe constitute first-line therapy, they provide less than optimal LDL-C reduction in severe FH.
  • In particular, homozygous FH requires combination therapy, high-dose statin and ezetimibe, with or without apheresis.

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Dr. prof frederick raal

Professor Raal is currently Professor and Head of the Division of Endocrinology and Metabolism, as well as Director of the Carbohydrate and Lipid Metabolism Research Unit, University of the Witwatersrand, Johannesburg, South Africa. Prof frederick raal is a Frederick J. Raal, MBBCh, FRCP, FCP(SA), Cert Endo, MMED, PhD Head, Division of Endocrinology & Metabolism Director, Carbohydrate and Lipid Metabolism Research Unit Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

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