Published On: 17 Aug, 2022 3:42 PM | Updated On: 27 Dec, 2024 6:34 AM
LAI Recommendations for the Use of Bempedoic Acid
- Studies show 15% to 25% LDL-C reduction on background statin therapy; higher LDL-C reduction in patients not on statins.
- Combination of bempedoic acid and ezetimibe lowers LDL-C by about 35% to 40%.
- Bempedoic acid not activated in muscle.
- Overall good safety profile: uric acid increase, small increased incidence of tendon rupture. Pending CV outcomes study.
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