Managing Acne Vulgaris While Pregnant or Breastfeeding

Acne vulgaris is a common problem for women during pregnancy and lactation due to hormonal and physiological changes that occur during these stages. Many effective acne treatments for the general population are not recommended during pregnancy or breastfeeding, yet guidelines for managing acne in these populations are limited. The present review summarizes the safety and efficacy of various acne treatments during pregnancy and breastfeeding. The approach to managing acne during these stages should consider the severity of the condition to reduce the risk. Topical therapies like benzoyl peroxide, azelaic acid, or keratolytic are suitable for mild-to-moderate cases. For moderate-to-severe acne, systemic treatments, including penicillin, amoxicillin, cephalexin, and erythromycin, may be appropriate, but it is crucial to consider the teratogenicity of the drugs and relevant medical history of the mother and infant. For cases that are not responsive to other treatments, oral or intralesional corticosteroids, as well as laser and light therapies, may be considered. This review serves as an updated reference to assist physicians in making decisions about managing acne in pregnant and lactating patients.

Ly S, Kamal K, Manjaly P. et al. Treatment of Acne Vulgaris During Pregnancy and Lactation: A Narrative Review. Dermatol Ther (Heidelb).2023; 13:115–130. https://doi.org/10.1007/s13555-022-00854-3