Non-HDL Cholesterol

• ASCVD risk remains high in patients who have attained the guideline – recommended LDL-C goals.

• In some circumstances like diabetes, obesity or very low LDL-C, it may underestimate the risk conferred by other apoB-containing lipoproteins.

• In these conditions, the simple calculation of non-HDL-C captures all apoB-containing lipoproteins, including remnant cholesterol.

• LAI recommendations-2020

• Non-HDL-C is a co-primary target

• Elevated apoB is a moderate nonconventional risk factor (a level >110 mg/dL of apoB corresponds to an LDL-C >130 mg/dL).

LDL Cholesterol

Has Limitation Overall

Non-HDL-C

Is The First Choice You See

For Now, ApoB

Has To Stay As Option B!