Pediatric Fatty Liver Disease

Pediatric Fatty Liver Disease

NAFLD is the most common chronic liver disease across all age groups with a prevalence of 9.6% in lean and 38% to 45% in obese children, respectively. It is commonly seen in small-for-gestationalage and large-for-gestational-age infants, and children born by obese or diabetic mothers. It should be suspected in obese ≥9 years of children, overweight children with a family history of NAFLD, or with cardiometabolic risk factors. For diagnosis, ALT levels are tested for initial screening, which can be later confirmed with vibration-controlled transient elastography. Some of the tips to manage pediatric fatty liver disease are:
  • Counseling against binge drinking, smoking, use of electronic nicotine delivery device. 
  • Families of children with NAFLD should be counseled about the risk of second-hand smoking exposure.
  • Ensure protection against Hep A and B.
  • Lifestyle modifications: Encouraging a balanced and healthy diet, regular moderate to high-intensity physical activity, avoiding sugar-sweetened beverages and limiting screen time.
  • Medications: No proven therapy.
  • Bariatric surgery can be considered in select patients. Hereditary fructose intolerance, lysosomal acid lipase deficiency, dyslipidemia, citrin deficiency and Wilson disease may present as fatty liver. But they should be seen as a red flag to prevent any future morbidity.

Dr. Aabha Nagral

Dr. Aabha Nagral is a senior consultant at Apollo and Jaslok Hospitals in Mumbai. She also runs her private clinic - Nagral clinic in Prabhadevi area, Mumbai. She is a Gastroenterologist by training from KEM Hospital, Mumbai with specialisation in liver diseases adult and pediatric and liver transplantation from Royal Free Hospital and Kings College Hospital, London UK and Mayo Clinic, USA. She is currently the chairperson of the liver committee of the ZTCC (Zonal transplant co-ordination committee), Mumbai and a liver committee member of the ROTTO-SOTTO. She is a managing trustee of Childrens Liver foundation an NGO working towards creating awareness about liver disorders in children and helping families of affected children financially and through support groups.

 More FAQs by Dr. Aabha Nagral


Medtalks is India's fastest growing Healthcare Learning and Patient Education Platform designed and developed to help doctors and other medical professionals to cater educational and training needs and to discover, discuss and learn the latest and best practices across 100+ medical specialties. Also find India Healthcare Latest Health News & Updates on the India Healthcare at Medtalks