Platelet Rich Plasma in Gynecology: Discovering Undiscovered

Platelet-rich plasma (PRP) is one of the most commonly used preparations in regenerative medicine. Regenerative medicine combines elements of molecular biology and tissue engineering. This aims to support the regeneration and repair processes of damaged tissues, cells, and organs.

PRP is advantageous as it can be obtained quickly and at a low cost. This treatment is now widely used in various fields of medicine. A recent review describes the use of PRP in gynecology and obstetrics. 

Undoubtedly, the released growth factors and proteins have a beneficial effect on wound healing and regeneration processes. Its most comprehensive application is in reproductive medicine, particularly in cases of thin endometrium, Asherman’s syndrome, or premature ovarian failure (POF). It is also used in wound healing and lower urinary tract symptoms (LUTS), such as urinary incontinence or recurrent genitourinary fistula auxiliary treatment. 

Special interest should be focused on the regenerative potential of PRP in overactive bladder (OAB) and stress urinary incontinence (SUI) as those conditions affect > 30% of people. If this treatment proves effective, it would be a desirable treatment option pertaining to its low cost and minimally invasive application without any adverse reaction risks associated with drugs or foreign materials in surgical treatment. 

However, more research is required to ensure its efficacy and potential application in a variety of other disorders.

Source: Int J Environ Res Public Health. 2022 Apr 26;19(9):5284. doi: 10.3390/ijerph19095284. PMID: 35564681; PMCID: PMC9100365.