The Correlation between Chlamydia Trachomatis and Female Infertility: A Systematic Review

We still lack knowledge about the impact of Chlamydia trachomatis (CT) infection on female fertility since the level of evidence associating these factors is weak. Hence, a recent review better elucidated this matter. 

The study's authors searched the electronic database like Medline/PubMed for relevant studies in the previous five years. It searched for keywords like chlamydia trachomatis AND infertility; chlamydia trachomatis AND tubal alteration AND infertility; chlamydia AND low pregnancy rates. 

• After scrutinizing the available studies for relevancy, the authors included 17 studies for qualitative analysis. 
• Their systematic review verified the hypothesis that CT infection potentiates female infertility, as 76.47% of the included studies found a positive correlation between them. 

Thus there exists an important association between CT infection and female infertility. Therefore CT screening as a part of the infertility investigation routine is relevant and has a reasonable justification.

Passos LG, Terraciano P, Wolf N, Oliveira FDS, Almeida I, Passos EP. The Correlation between Chlamydia Trachomatis and Female Infertility: A Systematic Review. Rev Bras Ginecol Obstet. 2022 Jun;44(6):614-620. English. doi: 10.1055/s-0042-1748023. Epub 2022 May 16. PMID: 35576969.