The oral mucosa is subject to constant physical and chemical insults, resulting in the development of ulcerated lesions that are prone to infection, potentially hindering the healing process.

This study conducted an extensive review of both medical and dental literature to explore the application of povidone-iodine in the treatment of oral wounds. The findings revealed that povidone-iodine can effectively control local infection in a concentration-dependent manner, positively influencing the tissue repair process. Consequently, oral antiseptics emerge as a favorable option for managing oral lesions, offering the advantage of minimal risk associated with systemic toxicity and allergies, along with limited clinical evidence of bacterial resistance.

Source: da SilveiraTeixeira D, de Figueiredo MAZ, Cherubini K, de Oliveira SD, Salum FG. The topical effect of chlorhexidine and povidone-iodine in the repair of oral wounds. A review. Stomatologija. 2019;21(2):35-41. PMID: 32108654.