Diabetes has emerged as a major healthcare problem in India. According to the Diabetes Atlas published by the International Diabetes Federation (IDF), there are an estimated 77 million persons with diabetes in India in 2021 and this number is predicted to rise. Genetic predisposition combined with lifestyle changes, associated with urbanization and globalization, contribute to this rapid rise of diabetes in India. This means that the productivity of the youth of our country could be seriously affected. Due to these sheer numbers, the economic burden due to diabetes in India is among the highest in the world. So, in this series, let us get some expert opinions on the challenges in diabetes care in India, such as sheer number, lack of awareness, and inadequate control.